Celastrol CAS 34157-83-0

CAS:34157-83-0

Formula ya Molecular:C29H38O4

Uburemere bwa molekile:450.61

EINECS:636-472-5

Amagambo asa:CELASTROL(SH); CELASTROL; Celastrol (Tripterin); CELASTROL(P)(HAMAGARA); (20R)-3-Hydroxy-2-oxo-24-nor-D:A-friedoolean-1(10),3,5,7-tetren-29-oic aside; 2-Oxo-3-hydroxy-24-norfriedela-1(10),3,5,7-tetraene-29-oic aside; 2-Oxo-3-hydroxy-24-norfriedelane-1(10),3,5,7-tetraene-29-oic aside Celasterol

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Celastrol CAS 34157-83-0 ni iki?

Celastrol ntishongera mu mazi, ishongera muri dimethyl sulfoxide na anhydrous ethanol. Ikomoka ku bintu birwanya kanseri mu bimera nka Thunder God Vine na South Snake Vine mu muryango wa Celastraceae. Irinda proteasome neza, byemejwe ko itera apoptosis y'uturemangingo twa kanseri ibuza imikorere ya proteasome.

Ibisobanuro

Ikintu	Ibisobanuro
Aho kubira	645.7±55.0 °C (Byateganijwe)
Ubucucike	1.2
Aho gushonga	219-230°C
pKa	4.78±0.70 (Byateganijwe)
λmax	424nm (MeOH) (umucyo)
Uburyo bwo kubika	-20°C

Porogaramu

Celastrol ikoreshwa mu kugena/kumenya/gupima imiti, nibindi. Ingaruka z'imiti: Ifite ubushobozi bukomeye bwo kurwanya antioxydants, ingaruka zo kurwanya angiogenesis ya kanseri, n'ingaruka zo kurwanya rheumatoid. Irinda poroteyine ikomeye, byemejwe ko itera apoptosis y'uturemangingo twa kanseri ibuza imikorere ya poroteyine