SHIKONIN CAS 517-89-5 Shikonine
Ikirahure cy'umukara w'umuhengeri, aho gushonga kuri 147℃, kuzunguruka kw'amajwi αD20 = + 135° (benzene). Irashonga mu mavuta ya phenethyl ether, acetone, chloroform, methanol, ethanol, glycerol, amavuta y'inyamaswa n'imboga hamwe n'amazi ya alkaline, ntishobora gushonga mu mazi. Ibara rihinduka bitewe n'agaciro ka Ph, aho agaciro ka Ph ka 4-6 kaba umutuku, agaciro ka Ph ka 8 kaba umutuku, naho agaciro ka Ph ka 10-12 kaba umutuku. Irwanya urumuri neza, irwanya ubushyuhe n'irwanya ogisijeni, idahindagurika ku rugero runini, kandi irashya ry'umukara ryijimye iyo ikoreshejwe iron. Ifite ingaruka zimwe na zimwe zo kurwanya bagiteri.
| CAS | 517-89-5 |
| Andi Mazina | Shikonine |
| Isura | ifu y'umuhengeri |
| Ubwiza | 99% |
| Ibara | umuhengeri |
| Ububiko | Ububiko bw'ahantu hakonje kandi humutse |
| Pake | 25kg/umufuka |
| Porogaramu | Ibiryo |
(1) Ingaruka zo kugabanya glucose mu mubiri. Ikibabi cya comfrey na polysaccharide (A, B, C) bya comfrey bifite ingaruka zigaragara zo kugabanya glucose mu mubiri.
(2) Ingaruka za bagiteri Lithospermum igira ingaruka zo gukumira virusi ya Jingke 68-1 muri vitro, kandi igira ingaruka zo gukumira Staphylococcus aureus. Ingaruka za levoshikonin zo kurwanya virusi ya parainfluenza zakorewe ubushakashatsi hakoreshejwe uburyo bwa hemagglutination na cytopathique. Ibisubizo byagaragaje ko ifite uburozi buke mu rugero rwakoreshejwe mu igerageza, kandi ifite ingaruka zimwe na zimwe zo kurwanya virusi ya grippe muri vitro no kwica virusi ya parainfluenza mu buryo butaziguye.
(3) Ingaruka ku gufungana kw'amaraso: Gutera ibice bya shikonin (shikonin, acetylshikonin) mu nda y'umura ntibigira ingaruka ku gihe cyo gufungana kw'amaraso, ahubwo bishobora gukumira ingaruka za heparin ku kurwanya gufungana kw'amaraso.
(4) Ingaruka zo kurwanya ikibyimba. Comfrey extract ifite ingaruka zimwe na zimwe ku gice cya nyuma (G2 phase) cyo gukora ADN mu turemangingo twa Hela.
(5) Ingaruka zo kurwanya ikibyimba Shikonin ibuza ikwirakwira ry’uturemangingo, igatera apoptosis kandi igatuma ingirabuzimafatizo z’uturemangingo zifatwa n’imiti ya choriocarcinoma y’abantu (JAR/MTX) mu buryo bwa vitro. Igerageza ryerekana ko ubwinshi bwa shikonin bwiyongera uko dose itangwa. Kandi igihe cyongerewe, igipimo cyo gukumira ikura ry’uturemangingo turwanya imiti ya choriocarcinoma nacyo cyariyongereye cyane.
(6) Ingaruka ku ikorwa ry'imisemburo Ingaruka za shikonin ku mikorere y'umurongo wa hypothalamic-pituitary-gonadal mu mbeba z'inkumi z'inkumi zagaragaje ko urugero rw'imisemburo mu maraso mu itsinda rya shikonin rwari hasi cyane ugereranije n'iryo mu itsinda ryagenzuwe nabi, kandi nta tandukaniro rinini ryagaragaye ugereranije n'itsinda ryagenzuwe ryiza. Bigaragaza ko shikonin ishobora kubuza imikorere y'umurongo wa hypothalamic-pituitary-gonadal mu mbeba.
(7) Ingaruka zo kurwanya ogisijeni Bamwe mu bashakashatsi bapimye ubushobozi bwo gukuraho shikonin kuri superoxide radical (O2-) na 1,1-diphenyl-2-picrophenhydrazine radical (DPPH), n'ingaruka zayo kuri β- - Kubuza sisitemu yo kwiyanduza aside ya carotene/linoleic. Ibisubizo byagaragaje ko shikonin ifite ubushobozi bukomeye bwo gukuraho DPPH na O2-, kandi ifite ingaruka zigaragara zo gukumira sisitemu yo kwiyanduza aside ya β-carotene/linoleic. Ubushobozi bukomeye bwo kurwanya ogisijeni.
25kgs/ingoma, toni 9/igikoni cya 20'
SHIKONIN-1
SHIKONIN-2
