Sodium Stearyl Fumarate CAS 4070-80-8

URUBANZA:4070-80-8

Inzira ya molekulari:C22H41NaO4

Uburemere bwa molekile:392.56

EINECS:223-781-1

Synonyme:umunyu wa sodium; SODIUMMONO-STEARYLFUMARATE; Sodium stearyl 2-fumarate; Sodium stearyi fumarate; SODIUM STEARYL FUMARATE; sodium octadecyl fumarate;

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Ibicuruzwa

Niki Sodium Stearyl Fumarate CAS 4070-80-8？

Sodium Stearyl Fumarate ni ifu nziza yera. Gushonga muri methanol, hafi yo kudashonga mumazi. Sodium Stearyl Fumarate iboneka mugukora alcool ya stearic hamwe na anhydride ya manic, isomerizing ibicuruzwa biva mumunyu. Sodium Stearyl Fumarate ni amavuta ya hydrophilique akoreshwa nk'amavuta mu bikoresho bya farumasi. Irashobora gutsinda ibibazo byinshi bijyanye na magnesium stearate, nko gufata imiti nyamukuru no gusiga amavuta menshi; Gukora firime ikingira ibinini bya effervescent birashobora kunoza gusenyuka, guteza imbere guseswa, bityo bikongera bioavailability.

Ibisobanuro

Ingingo	Ibisobanuro
gushonga	> 196 ° C (Ukuboza)
Imiterere yo kubika	Ikirere cyimbere, Ubushyuhe bwicyumba
ubuziranenge	98%
LogP	8.789 (est)
ibara	Cyera kugeza cyera

Gusaba

Sodium stearate fumarate (C22H39NaO4) ni imiti ikoreshwa cyane kandi ikomeye yimiti nibiribwa. Mugihe cyimikorere ya metabolike ya sodium fumarate mubikoko, inyinshi murizo zirashobora kwinjizwa hamwe na hydrolyz kugirango zibyare inzoga ya stearic na aside stearic. Igice gito gishobora guhindurwa muburyo bwihuse kandi bwihuse, kandi ntabwo ari uburozi kandi ntiburakaza. Mu rwego rwa farumasi, sodium stearate fumarate yongewe kumiti nkibisiga amavuta ya tableti na capsules. Igitabo cy’imiti kirashobora kandi gukora firime ikingira ibinini bya effevercent, bishobora gukemura ibibazo byamavuta ya stearate no kunoza ibiyobyabwenge no guteza imbere ibiyobyabwenge. Mu nganda z’ibiribwa, FDA yemerera sodium fumarate stearate kongerwamo mu buryo butaziguye nkumuyobozi noguhindura ibiryo bigenewe kurya abantu, nkibicuruzwa bitandukanye bitetse, ibiryo byuzuye ifu, ibirayi byumye, nintete zitunganijwe. Ingano ya sodium fumarate yongeyeho irashobora kuba 0.2-1.0% byuburemere bwibiryo.