amakuru

I. Intangiriro

Unilong ni uruganda rw'umwuga rukora kandi rugatanga ibikoresho byo kwisiga bifite imikorere myiza, rutanga ishemaHinokitiol (CAS 499-44-5)– izwi kandi nka β-thujaplicin – mu buryo bwa sintetike kandi bufite isuku yo hejuru. Bitandukanye na hinokitiol karemano ikomoka ku biti bya Cupressaceae bike kandi bita ku bidukikije, hinokitiol yacu ya sintetike itanga imiterere imwe ya chimique n'imikorere ya biyolojiya hamwe n'ubwiza buhamye, itangwa rihamye, kandi ibiciro bihiganwa. Nk'umuti ukoresha imikorere myinshi ufite ubushobozi bwo kurwanya bagiteri, kurwanya mikorobe, kurwanya antioxidant, kurwanya ububyimbirwe, no kumurikira uruhu, hinokitiol yagaragaye nk'ikintu cy'ingenzi mu kwita ku ruhu muri iki gihe. Waba ukora imiti ivura ibiheri, imiti irwanya gusaza, imiti igabanya ubushyuhe, cyangwa uburyo bwo kongerera uburinzi ubuziranenge, hinokitiol ya sintetike ya Unilong itanga imikorere ukeneye hamwe n'ubwizerwe witeze.

II. Incamake y'ibicuruzwa

Hinokitiol (CAS 499-44-5), izwi kandi nkaβ-thujaplicin, ni ikintu karemano cy’ubwoko bwa monoterpenoid kibarizwa mu muryango wa tropolone. Cyari cyarakuwe mu giti cy’umutima cy’ibiti bya Cupressaceae nka hinoki ya Taiwan (Chamaecyparis taiwanensis) na cypress yo mu Buyapani (Aomori Hiba). Ifite formula ya molekile ya C10H12O2 n’uburemere bwa molekile bugera kuri 164.20 g/mol, hinokitiol ifite imiterere yihariye y’impeta ya tropolone ishinzwe ibikorwa byayo bitangaje by’ibinyabuzima.

III. Imikorere y'ingenzi n'Ibyiza

1. Igikorwa cyo kurwanya mikorobe mu buryo bwagutse

Hinokitiol igaragaza ingaruka zikomeye zo kurwanya mikorobe ku bwoko butandukanye bwa bagiteri, ibihumyo, ndetse na virusi zimwe na zimwe. Uburyo bwayo burimo guhungabanya ubusugire bw'uturemangingo binyuze mu kugabanya ingano ya ergosterol mu turemangingo tw'ibihumyo no kongera ubushobozi bwo kwinjira mu turemangingo. Ikigaragara ni uko hinokitiol yagaragaje ubushobozi butangaje mu kurwanya Staphylococcus aureus (MRSA) idakira Methicillin - indwara ikunze kugaragara ku ruhu rw'umuntu no mu myanya y'ubuhumekero ishobora gutera indwara zikomeye z'uruhu, sepsis, ndetse n'uburozi bw'ibiryo.

(1) Kurwanya bagiteri: Igira ingaruka nziza ku bagiteri za Gram-positive zirimo S. aureus na MRSA

(2) Kurwanya ibihumyo: Bikumira Aspergillus fumigatus, ubwoko bwa Candida, Aspergillus niger, na Penicillium citrinum

(3) Uburozi bwo guhitamo: Ubushakashatsi bwerekana ko hinotiol ikunda cyane uturemangingo twa bagiteri kurusha uturemangingo tw’uruhu rw’inyamabere, bigatuma ikoreshwa mu gushyira mu myanya yo mu gikoni.

2. Umurimo ukomeye wo kurwanya ogisijeni

Hinokitiol ikora nk'umuti ukomeye urwanya udukoko, ikangiza neza uturemangingo tw’umwuka dukomoka ku bidukikije n’ibintu bitera ubushyuhe. Mu kugabanya ubwoko bwa ogisijeni ikora neza (ROS), ifasha mu gukumira gusaza k'uruhu imburagihe, ikagabanya kwangirika kwa ogisijeni, kandi ikarinda uruhu ruzingira. Ubu bushobozi bwo kurwanya udukoko buzuza izindi nyungu z'uruhu, bigatuma iba ikintu cyuzuye kirwanya gusaza.

3. Kugenzura imiterere irwanya ububyimbirwe

Uretse ingaruka zo kurwanya indwara ziterwa na antioxydants, hinokitiol ifite ubushobozi bukomeye bwo kurwanya ububyimbirwe. Ubushakashatsi bwagaragaje ko ifite ubushobozi bwo guhindura inzira zo kubyimbirwa, harimo n'inzira ya TLR4/MyD88, bigatuma igira akamaro mu kugabanya ububyimbirwe buterwa na dermatitis ya atopic (eczema) n'izindi ndwara z'uruhu ziterwa n'ububyimbirwe. Ibi bituma hinokitiol igira akamaro kanini ku bwoko bw'uruhu rworoshye kandi rushobora kwangirika.

4. Kurabagirana k'uruhu no gukumira melanin

Hinokitiolbyagaragaye ko bibuza ikorwa rya melanin binyuze mu kugabanya imikorere ya tyrosinase, ikora nk'ikintu gitanga urumuri rw'ibinyabuzima ku duce twijimye, uduce tw'ubusaza, no gukurura ibara ry'uruhu. Iki gikorwa kibiri - gitanga urumuri ariko gitanga akamaro ko kurwanya udukoko no kurwanya ububyimbirwe - gituma kiba ikintu kidasanzwe mu kunoza uruhu rwose.

5. Ibyiza byo kwangiza icyuma n'uturemangingo

Nk'umuti urinda icyuma, hinokitiol ishobora guhindura urugero rw'icyuma mu turemangingo - umwihariko wagaragaye ko ufite ingaruka nziza ku ihinduka rya keratinocyte n'ubuzima bw'uruhu muri rusange. Ubu buryo budasanzwe bwongera ikindi kintu ku miterere yabwo myinshi.

6. Kongera ubushobozi bwo kubungabunga ibintu mu buryo bw'umwimerere

Imiterere ya Hinokitiol yo kurwanya mikorobe ituma iba uburyo bwiza bwo kongera ubuziranenge mu miterere y’ubwiza. Ishobora kugabanya kwishingikiriza ku miti irinda uburozi, igashyigikira "ubwiza busukuye" n'ibicuruzwa "bitagira ubuziranenge" mu gihe ikomeza umutekano wa mikorobe.

IV. Uturere tw'ingenzi dukoreshwa

1. Kurwara ibiheri n'uruhu rushobora kwangirika

HinokitiolYagaragaje ubushobozi budasanzwe mu kuvura ibiheri, eczema, n'izindi ndwara z'uruhu ziterwa n'ububyimbirwe binyuze mu kugabanya gukura kwa mikorobe mu gihe icyarimwe igabanya ububyimbirwe. Ikora neza cyane mu kurwanya bagiteri zitera ibiheri (harimo na C. acnes na S. aureus) ifasha kugabanya ibibyimba no guteza imbere uruhu rwiza. Imiterere yo kurwanya ububyimbirwe irushaho gufasha gutuza ibisebe biriho no gukumira ububyimbirwe bukabije nyuma yo kubyimbirwa.

2. Kurwanya gusaza no kuvugurura uruhu

Binyuze mu bikorwa byayo bikomeye byo kurwanya imisemburo mibi, hinokitiol ifasha mu kugabanya udukoko twitwa "free radicals" dutuma umuntu asaza imburagihe. Ituma uruhu rusa neza, ikagabanya iminkanyari n'iminkanyari, kandi igatuma uruhu rusa neza. Ubushobozi bwayo bwo gushyigikira ubuzima bw'uruhu mu gihe irinda imirasire y'izuba burushaho kongera agaciro kayo mu miti irwanya gusaza.

3. Gutanga uruhu rwiza kandi rufite ibara ringana

Ubushobozi bwa Hinokitiol bwo kubuza ikorwa rya melanin butuma iba ikintu cy'ingenzi mu gukarisha no gutunganya amabara. Ifasha uruhu kumera neza, ikagabanya isura y'uduheri twijimye n'uduheri dusaza, kandi igatuma uruhu rusa neza. Ibi bituma iba nziza cyane iyo ivanzwe n'ibindi bintu bitanga urumuri kugira ngo irusheho kugira ingaruka nziza.

4. Kwita ku ruhu no kuvura eczema

Imiterere ya Hinokitiol yo kurwanya ububyimbirwe hamwe n’imikorere yayo irwanya udukoko itera indwara ituma iba nziza cyane ku ruhu rworoshye. Ubushakashatsi bwagaragaje ko ifite akamaro mu kugabanya ububyimbirwe mu bwoko bwa atopic dermatitis. Bitandukanye n’imiti ikomeye irwanya udukoko ishobora kwangiza mikorobe z’uruhu, hinokitiol itanga uburyo bworoshye ariko bufite akamaro bwo kuvura indwara z’uruhu zoroshye kandi zitera indwara.

5. Kwita ku gahanga no ku musatsi

Imiterere ya Hinokitiol yo kurwanya udukoko no kugabanya ubushyuhe igera no mu bikorwa byo kwita ku ruhu rw'umutwe. Ifasha kurwanya ibihumyo bitera uruhu rw'umutwe, igabanya uburibwe bw'umutwe, kandi igateza imbere ahantu heza ho ku ruhu rw'umutwe - byose ni ingenzi kugira ngo umusatsi ukure neza kandi usa neza.

6. Kwita ku kanwa

Hinokitiol yakoreshejwe mu miti yo koza amenyo no mu kanwa kubera ubushobozi bwayo bwo kurwanya bagiteri. Ifasha kugabanya bagiteri zo mu kanwa, ikarinda kwirema kwa plaque, kandi ikarushaho guteza imbere ubuzima bw'ishinya.

7. Uburyo bwo kubungabunga ibintu karemano

Nk'umuti ufasha mu kubungabunga ibidukikije karemano, hinokitiol ishobora gushyirwa mu miti ifasha mu kongera ubushobozi bwo kubungabunga ibidukikije mu gihe ishyigikira ibivugwa mu "cyubahiro gisukuye". Ikorana neza n'indi miti irinda impanuka, bigatuma ingano y'imiti irinda impanuka igabanuka.

V. Ibisobanuro bya tekiniki

VI. Incamake

Waba urimo gukora imiti yo kuvura ibiheri, serumu zirwanya gusaza, imiti igabanya ubushyuhe, imiti yo kwita ku mutwe, cyangwa uburyo karemano bwo kubungabunga uruhu,Hinokitiol yakozwe na Unilong(≥99%) itanga imikorere myinshi y’imiti yawe ikenewe - hamwe n’ubwizigirwa bw’ingufu n’uburyo ikoreshwa mu gukora sintetike ritanga.

Twandikire uyu munsi kugira ngo ubone ingero, impapuro z'amakuru ya tekiniki (TDS), cyangwa impapuro z'amakuru y'umutekano (SDS)!